COVID-19 Delta Variant

By Gwamaka Mwakyusa – Art in Tanzania internship

Delta variant, a strain of Covid-19 that wreaked havoc during India’s second wave, has been identified in at least 85 countries. According to the World Health Organization (WHO), the delta covid variant is the most transmissible of all the variants identified so far. Acknowledging the contagious nature of the delta Covid-19 variant that was first identified in India, the WHO on June 25 urged vaccinated people to continue wearing masks.

The delta variant, or B.1.617.2, which was first identified in India in October 2020, has now become the dominant strain in the UK, currently accounting for more than 90% of coronavirus cases there. Meanwhile, in the US, the delta variant accounts for more than a third of new cases, according to Financial Times analysis. The former commissioner of the US Food and Drug Administration, Dr. Scott Gottlieb told ‘CBS News’ Face the Nation’ that the United States is likely to witness “very dense outbreaks” due to the delta variant.

The US Centers for Disease Control and Prevention (CDC) estimates that delta accounted for 20.6% of all Covid-19 cases between June 5 and June 19.

This surge has led Dr. Anthony Fauci, chief medical advisor to the White House, to label the variant as the “greatest threat” to the country’s attempt to eradicate Covid-19.

Both the UK and US have high vaccination rates, and it remains to be seen whether their populations are protected against this Covid strain. But in much of the rest of the world, where Covid-19 vaccines have not been administered at the same level, the concerns are even greater.

Covid delta variant on WHO’s radar

On June 25, the World Health Organization’s Dr. Maria Van Kerkhove in a press conference said that the delta variant is a dangerous virus. “It is more transmissible than the Alpha variant, which was extremely transmissible across Europe, across any country that it entered. The Delta variant is even more transmissible,” she explained during the conference.

Thus far, there are four “variants of concern” flagged by the WHO and seven “variants of interest.” Despite the strain being identified last year, the delta variant was tagged as a variant of concern only on May 11. This is because the WHO uses three parameters—increased transmissibility, more virulence, and decreased effectiveness of public health measures—to determine its seriousness.

The delay is also because there wasn’t enough genome sequencing data coming from India during its brutal second wave. Now, data from the Public Health England (PHE), the UK government’s health executive arm, have given scientists and public health experts around the world some ability to make sense of this Covid-19 variant.

What is the delta variant?

When Covid-19 infections broke out in Wuhan, China, that first strain was a “wild type” virus. This was the strain used by scientists across the world to develop testing kits, treatment plans, and even Covid vaccines.

It is in the nature of viruses to mutate, and it did. But not all mutations are serious, and usually do not require countries to reimagine their public health measures.

The variants of concern—Alpha (first identified in the UK), Beta (South Africa), Gamma (Brazil), and Delta—are different from all other countless variants for this very reason.

The delta variant has certain significant mutations in the spike protein of the virus—the pointy elements that give it the shape of a crown (which is why it’s called the coronavirus). These spikes are like hooks that have to find the receptors in a human cell to link with. Studies have shown that these spikes hook onto receptors called ACE-2. Once these spike proteins can unlock the cells, the infection spreads by replicating the genetic code of the virus.

Some key mutations in the delta variant—such as the E484Q, L452R, and P614R—make it easier for the spikes in the virus to attach to ACE-2 receptors. This means it can infect and replicate faster, and even evade the body’s natural disease-fighting immunity more efficiently.

The spike protein mutations make the delta variant the “fastest and fittest” variant yet, according to the WHO. The disease caused by this variant might also exhibit different symptoms than other viral mutations. Those infected with the delta variant develop symptoms such as headaches, sore throat, and a runny nose, replacing cough and loss of taste or smell like the most common symptoms.

Is the delta variant more transmissible?

“Most studies indicate delta is 50-60% more transmissible than the Alpha variant,” says Dr. Bhramar Mukherjee, associate director for quantitative data sciences at the University of Michigan Rogel Cancer Center. “The Alpha variant itself was nearly 50-60% more transmissible than the original strain.”

This, according to Mukherjee, implies that if the reproduction number for the original strain was around 2.4-2.6, the one for Alpha is 3.6-4.2, and for delta, it is 5.6-6.7. In layman terms, if a person infected with the original strain could infect nearly two people, a person with the Alpha variant could infect four people. With delta, one person could infect nearly seven other people. It’s important to remember that these are averages, not absolute numbers; one delta carrier might infect zero people, or 25.

Its higher reproduction number is likely why entire families in crowded Indian cities like Delhi and Mumbai were infected together. It would also explain the tsunami-like surge of cases in the country in April and May.

The other consequence of a higher reproduction number (denoted as R in epidemiological data) in an epidemic is that it increases the threshold for herd immunity. That is, more people will need to have the antibodies—either through infection or vaccination—to be protected as a community against the delta variant. “With an R of 2.5, the threshold for herd immunity is 60%, but with an R of 6, it is 83%,” explains Mukherjee.

Do vaccines work against the delta variant?

According to the CDC, studies show that the currently authorized vaccines which include Pfizer-BioNTech, Moderna, and Johnson&Johnson or Janssen work on the circulating variants.

Dr. Gautam Menon, professor at the departments of physics and biology at Ashoka University in India said, “It is reasonably certain that the delta variant also exhibits some immune escape, although estimates vary as to the extent.” For instance, single doses of Covid-19 vaccines, according to data from the UK, are only 33% efficacious against the disease.

But there is hope that those who are fully vaccinated are reasonably protected against serious disease. According to data from PHE, Pfizer’s mRNA vaccine is 96% effective, and the AstraZeneca vaccine 92% effective against hospitalizations after two doses. These, PHE says, are comparable to efficacy against the Alpha variant.

This also means that getting a large part of the population fully vaccinated is crucial for countries where the delta variant is prevalent. For countries like the US, where nearly half the population is fully vaccinated, scientists suspect a varied impact of the delta variant. “I would expect some breakthrough infections and transmission happening even in highly vaccinated areas in the US, but would not expect a spike in hospitalizations and deaths,” Mukherjee says.

“We cannot be complacent with a large percentage only partially vaccinated, dropping masks and Covid-appropriate behaviors,” she adds. “We need full vaccination for a large fraction to fight the delta variant.” She also expects that in pockets of the US with lower vaccine coverage, cases of delta variant could rise.

Experts from WHO reiterated that the delta variant is spreading rapidly among unvaccinated populations. However, the health agency quickly noted that “vaccines are effective at preventing severe disease and death, including against the delta variants.

Can masks keep the delta variant in check?

Public health experts are investigating whether booster shots of vaccines will be needed to protect the population against the new variant.

Hence, the WHO is once again highlighting the need to wear masks. “Vaccine alone won’t stop community transmission,” said Mariangela Simao, the WHO’s assistant director-general for access to medicines and health products, during a briefing at the organization’s headquarters in Geneva. “People need to continue to use masks consistently, be in ventilated spaces, [practice] hand hygiene, [maintain] physical distance, avoid crowding,” she said,

Although Covid cases in the US have been steadily declining as vaccination rates are going up, it might be reaching an impasse. Joe Biden had set a target of immunizing 70% of adult Americans by July 4, but the country will fall short, reaching 67% of all eligible adults. Some 20% Americans say they don’t want to get the vaccine.

What is the delta plus variant?

The delta variant has developed a new mutation of a type that was first found in the Beta variant. The new variant—which is being labeled delta plus, though not officially by the WHO yet—additionally has the K417N mutation in its spike protein, which is associated with increased immunity escape.

Shahid Jameel, a top virologist in India, has said that delta plus could also render cocktail antibody treatments—like the one given to former US president Donald Trump—ineffective in fighting the disease. This variant could also potentially lead to vaccines being less effective. India has officially flagged delta plus a “variant of concern,” though after a great deal of indecision.

Menon says the delta plus variant is not a cause for worry yet but would be “if it began to replace the existing variants.” “Currently, there is no evidence that this is the case,” he says, “so there is no cause for immediate worry, but this may change, and we should be watchful for this.”

Mukherjee warns that India, where 40% of the population is below the age of 17 and not eligible for vaccines, needs to adhere to strong public health interventions to control the coronavirus pandemic. Besides scaling up vaccinations, she suggests better studies around the variants, an area where India has been particularly slow. “We need to study properties of these variants: what the clinical manifestations are, whether our diagnostic tests work well to detect them, whether treatments work well.”

The delta plus variant has now been detected in at least nine countries, including the UK, US, China, and Japan.

The Effect of COVID – 19 on African Tourism

By Dilyara Shantayeva – Art in Tanzania internship

Tourism is an important economic sector for Africa. According to the United Nations World Tourism Organisation, Africa received 71.2 million international arrivals in 2019 amounting to about US$ 40 billion in revenue. This represents a 4 percent growth in arrivals over that of the previous year. Tourism has witnessed sustained growth on the continent as governments continued to pursue it as a viable economic option due to its contribution in terms of jobs, revenue, foreign exchange, and infrastructure.

Africa is increasingly becoming a preferred destination for many international tourists looking to enjoy its sunny beaches, ecotourism products, national parks and safaris and exotic culture and food. Unfortunately, the projected growth of between 3 to 5% in international arrivals for the continent cannot be realised: like every continent, Africa’s tourism industry is shattered, and the inflow of the tourist dollar has ceased due to the impact of COVID-19. The highly contagious spread of the coronavirus ultimately stopped most of the traveling to many touristic destinations is still causing many discrepancies these days as well. This article will overview the main effects of COVID – 19 on African tourism.

“We live in very challenging and uncharted waters at the moment,” says Nigel Vere Nicoll, President of the African Travel and Tourism Association (ATTA), an organization which he founded 25 years ago. ATTA has around 700 members in Sub-Saharan Africa, split relatively evenly between buyers – such as tour operators – and suppliers (hotels, lodges, and transportation companies). In the interview with the journalist from the Africa Outlook, he mentioned that one of the biggest problems currently facing the industry is confusion over cancelled bookings. Travellers who’ve already booked the tours and tickets and the situation have changed very rapidly, they have loads of questions concerning refunds, re-bookings, and other related issues.

He also mentioned the economic issues that Africa had encountered during the pandemics: “Take one small boutique lodge in Africa with, say, 10 rooms,” he says. “They would employ about 50 people, but their extended suppliers – so, the person who does the laundry, or brings in the eggs every day – probably equates to around 1,000 extra people. If that lodge packs up, then 1,000 people have no income.”

There are also other, less obvious effect: In Kenya, for example, many conservancies have been established on land belonging to the Masai Mara peoples. They remove their grazing cattle from the land and lease it to organisations building safari lodges that conserve it for wildlife, the revenue from tourists providing an income to the Masai people.

“That model works fine until there’s a nonessential travel warning, and then no money is coming in and they can’t pay the Masai,” Vere Nicoll adds. “One my closest friends has just been to see one of the chiefs and explained the situation, telling him ‘we’re going to go on paying you out of reserve funds, but we don’t know how long this is sustainable for.’

“If this goes on for a long time, all this work on conservancies will be put in jeopardy, because if the Masai don’t get revenue then their livelihood is at stake.”

So, what is the solution? How can the African tourism industry keep going?

Vere Nicoll believes the answer lies in domestic tourism. As there are such low levels of COVID-19 within many African countries now, travel is still possible.

“It’s not possible to cross borders within Africa, because they all have the same warning on, but it is possible to create domestic tourism,” he explains. “In fact, this is an amazing opportunity to create cashflow for survival with the local market. Kenya, for example, has a huge number of Europeans living within the country, who could become domestic tourists.”

Another saving grace is that it’s currently low season in East Africa, so tourism companies and hotels in that area anticipate having fewer customers this time of year. Some smaller safari lodges are even closed, ready to reopen for summer’s high season.

“What we are hoping is that tourism will recover in the English autumn, and they’ll have the chance to get some bookings in the late season, leading up until Christmas,” Vere Nicoll says. “If it lasts any longer, we’re in a totally different ball game.”

However, he concludes our conversation on a note of optimism. “The bottom line is that the tourism industry is very resilient. It always has been. We’ve been through many problems over the years, especially in eastern and southern Africa, and we’ve always come through in the end.

“I think the industry will come out of it much stronger. A lot of relationships will be built up. And I think that once the coronavirus goes, if it’s a short-term thing, then the industry will bounce back tremendously.”

In general, the tourism industry has been heavily impacted by the pandemic as people’s economic lives are halted and their freedom of movement curtailed. Chiefly among these impacts on African economies is the reduction in foreign income. With the closure of the world economy and the associated redundancy as well as closure of international borders, international tourist inflows into Africa have ceased.

The United Nations World Tourism Organisation (UNWTO) indicates that international tourist arrivals to Africa decreased by 35% between January to April 2020 as a result of the pandemic. Countries such as Gambia, South Africa, Egypt, Kenya, and a host of others that are heavily dependent on the expenditure of international tourists have witnessed dwindled injections of tourism-based foreign income. Equally, and associated with this, is the closure of tourism businesses. Tourism businesses are forced to close either because of internal measures to help stop the spread of the coronavirus or directly because of the absence of tourists.

Either way, the closure of tourism businesses such as hotels, attractions, travel and tour operations, food and beverage services, and other support businesses have resulted in massive job losses across the tourism industry in Africa. Both direct jobs that are primarily targeted at serving tourists and those in the value chain have all been impacted.

Ultimately, the closure of tourism businesses coupled with massive job losses have resulted in the reduction of corporate and individual income tax revenue to African governments and thereby affected their abilities to provide the required public services and infrastructure. Such tourism-dependent African economies are therefore compelled to increase their borrowing, thereby spiraling their debt burden and potentially perpetuating their poverty cycle. For instance, South Africa, a country with a significant tourism sector, for the first time in its history took a loan of US$ 4.3 billion from the IMF. Interestingly, this amount is less than its annual foreign income from the tourism industry.

Similarly, countries like Ghana that has tourism as its fourth foreign income earner, contributing more than over US$ 1 billion a year, have contracted a US$ 1 billion loan facility from the IMF. This has become an all too familiar story across the continent with many African countries with significant tourism industries losing out on tourist dollars.

While tourist dollars have stopped flowing to the continent, for the time being, there is hope, with the UNWTO indicating that confidence in recovery in Africa remains very strong compared to other world regions.

To achieve this, there is the need for the gradual easing of lockdown measures, including the opening of international borders, to allow the inflow of international tourists. Also, African governments should institute safety protocols to guarantee the safety of both tourists and employees at the ports of entry into individual countries, and at tourism facilities and attractions. And African governments through their national tourism organizations can begin to bundle their tourism products to reduce the cost of travel.

The bundling can be done to cut profit margins on individual tourism elements and therefore reduce the overall cost. This will also have the advantage of compelling tourists to visit many attractions and stay longer and thereby spend more at destinations. Tourism facilities can also offer discounts or complementary services to entice customers, especially domestic tourists at the initial stages of re-opening.

Further, there should be aggressive marketing of African destinations in international circles to re-assure Western and, to some extent, Chinese tourists about visiting Africa once more. Lastly, African governments can offer tax exemptions and holidays to tourism businesses to help them recover from the consequences of the pandemic. Such tax holidays and exemptions will help them grow back their earnings into their businesses to recover and grow in the short term.